A single type of chemical structure that shows up again and again in modern medicine is the amide bond that links a carbonyl ...

A high-yield, one-pot, scalable reaction facilitates the production of biologically relevant amide compounds using less reactive nitrogen-containing heterocyclic compounds and carboxylic acid without ...

The authors’ approach is deceptively simple: take an aldehyde dehydrogenase enzyme, which naturally converts aldehydes to acids, and get it to react with an amine instead of water. But actually making ...

Nuclear Magnetic Resonance (NMR) spectroscopy is a useful tool for exploring various domains across the natural sciences. NMR is well-suited to the analysis of molecular properties, such as the amide ...

Medicines come from chemical reactions, and better chemical reactions lead to better medicines. Yet, the most popular reaction used in drug discovery, called the amide coupling, makes an inherently ...