August 26, 2009 — Intramuscular injection treatment of an antisense molecule is safe and effective in increasing dystrophin, the absence of which causes Duchenne muscular dystrophy (DMD), according to ...

Cold Spring Harbor Laboratory researchers have reported that a bespoke antisense oligonucleotide can disrupt alternative splicing of Aurora kinase A, which has collapsed a feedback loop that ...

Courtesy of Antisense Therapeutics Ltd. Antisense strategies use polymeric nucleic acids or nucleic acid analogs to bind to and silence specific messenger RNAs. The silencing can be caused either by ...

Assessing the distribution of a medication in the brain is critical for the treatment of a vast range of neurological disorders, especially conditions such as Parkinson's and Alzheimer's diseases. To ...