Powerful white blood cells referred to as CD8 killer T cells enable the body to control infections and fight cancer. But when they become exhausted, they can become dysfunctional and ineffective.

A Brossay Lab study reveals how nonclassical CD8+ T cells can be activated by molecules that go undetected by classical CD8+ ...

Scientists uncover a new “recipe” that shows how exhausted T cells can be reprogrammed to regain their ability to attack tumors.

A multi-institutional study led by researchers at UNC Lineberger Comprehensive Cancer Center, the Salk Institute for Biological Studies, and UC San Diego has uncovered new genetic rules that determine ...

Scientists have discovered key genetic factors that determine whether a T cell acts as a powerful disease fighter or enters ...

Immune Checkpoint Blockade (ICB) has revolutionized the treatment of cancers like melanoma, but up to 60% of patients don't ...

After months of shrinking scans, the tumors suddenly came roaring back. Oncologists have seen this pattern for years in ...