Historically, the centrosome has been linked to cell-cycle control and its role in cancer has been studied extensively. More recent evidence has shown, however, that the centrosome is also involved in ...
In many types of cancers, centrosome amplification is observed at a high frequency and is associated with poor patient outcomes 1,2,3,4,5. Centrosome amplification is thought to be caused by both ...
Researchers have solved an important puzzle in neurobiology: the wiring and the movement of nerve cells are interwoven, but separately controlled. The study focuses on neuronal growth and migration: ...
Intra-patient genomic heterogeneity of single circulating tumor cells (CTCs) associated to phenotypic CTC heterogeneity in metastatic castrate resistant prostate cancer (mCRPC). SOD2 rs4880 CT/CC ...
In humans and other mammals, cardiac muscle cells stop replicating soon after birth, unlike the cardiac muscle cells in, say, zebrafish and amphibians. What do zebrafish and amphibian cardiomyocytes ...
Centrosomes are small structures in cells with many essential functions, including roles in cell signaling and in organizing a cell’s cytoskeleton. Centrosome dysfunction contributes to diseases like ...
Clinical applications of genetic sequencing in lymphoma: A retrospective review. Concordance of PD-L1 expression detection in non-small cell lung cancer (NSCLC) tissue biopsies between OncoTect iO ...
Le centrosome est un centre organisateur des microtubules (ou MTOC). Il est donc responsable de la formation du fuseau mitotique microtubulaire lors de la division cellulaire, sur lequel se déplacent ...
Damage to the human heart causes cardiac muscle cells to die, which in turn leads to reduced heart function and death. However, this is not the case for zebrafish or amphibians. If their hearts become ...
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