How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But ...

Genetic information encoded in genomic DNA is transcribed to mRNAs and then the codons on mRNA are decoded by transfer RNAs (tRNAs) during protein synthesis. tRNAs deliver amino acids to ribosomes and ...

In eukaryotes, there are four rRNAs associated with ribosomes; these are the 18S, 5.8S, 28s, and 5S rRNAs. Production of the first three occurs within the nucleolus, whereas 5S rRNA production occurs ...

Nuclear-encoded regulatory proteins control mitochondrial translation. A few, however, are encoded by the mitochondrial DNA (mtDNA) and are produced by the mitochondrial translation machinery.

In a step toward treating mitochondrial diseases, researchers at the University Medical Center Utrecht and their colleagues have used mitochondrial base editing (mtBE) to successfully edit harmful ...

Bacteria contain a wide variety of mechanisms to fend off invaders like viruses. One of these strategies involves cleaving transfer ribonucleic acids (tRNA), which are present in all cells and play a ...