Researchers at Nagoya University in Japan have developed a lipid nanoparticle that delivers mRNA to cells five times more effectively. By attaching a sulfur-containing ring structure—a cyclic ...

Scientists have developed stable orally available cyclic peptides with a much higher bioavailability than current ones, virtually creating a generation of drugs that can target previously untreatable ...

Scientists at the Ecole Polytechnique Fédérale de Lausanne (EPFL) have addressed a long-standing challenge in the pharmaceutical industry, with the development of a two-step, one-pot method for ...

Certain types of peptides and microproteins for drug discovery research can be made more efficiently and quickly using a reaction solvent that helps mimic nature's way Cysteine is one of the many ...

Drug discovery demands speed and precision, with success often hinging on how quickly teams can move compounds through synthesis, purification, and testing. In this project, flexibility and agility ...

The modified lipid nanoparticle (CDL-LNP) contains several ingredients that work together to deliver mRNA effectively: the mRNA payload with genetic instructions, standard lipid molecules (ionizable ...