A single type of chemical structure that shows up again and again in modern medicine is the amide bond that links a carbonyl ...
The synthesis and subsequent functionalisation of amides have emerged as pivotal areas in modern synthetic chemistry, enabling the direct conversion of these otherwise inert functional groups into ...
Amide bonds are common in drugs because they are chemically stable, form readily and are biocompatible. They also help ...
Amides are among the most ubiquitous functional groups in organic chemistry, forming the backbone of peptides and playing a vital role in pharmaceutical, synthetic and materials chemistry. Their ...
Professor Pei-Qiang Huang's research group at Xiamen University recently reported the first reduction-cross-coupling reaction of aliphatic tertiary ...
A platform to engineer enzymes responsible for the formation of amide bonds as an effort toward developing biocatalysts for green chemistry. Amide bonds — a type of chemical bond formed between a ...
Researchers at the Biocatalysis group led by Dr Francesco Mutti at the Van ‘t Hoff Institute for Molecular Sciences (University of Amsterdam) have developed a novel use of alcohol dehydrogenase (ADH) ...
The authors’ approach is deceptively simple: take an aldehyde dehydrogenase enzyme, which naturally converts aldehydes to acids, and get it to react with an amine instead of water. But actually making ...
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