Please provide your email address to receive an email when new articles are posted on . Efgartigimod, a human IgG1 antibody designed to decrease pathogenic IgG autoantibody levels, demonstrated ...
The lower hinge of immunoglobulin G (IgG), an overlooked part of the antibody, acts as a structural and functional control ...
In human filariasis, the predominant serum antibody is IgG4, accompanied by significant IgE production. The ratio of IgG4 to IgE is highest in asymptomatic microfilaremic carriers, while chronic ...
Effect of denileukin diftitox (DD) on vaccine-induced T-cell responses and depletion of Tregs in melanoma. This is an ASCO Meeting Abstract from the 2015 ASCO Annual Meeting I. This abstract does not ...
Marking Techniques for Target Lymph Nodes in Node-Positive Breast Cancer Treated With Neoadjuvant Therapy in the AXSANA/EUBREAST-03/AGO-B-053 Study Apparently, nothing was wrong in the clinical ...
The researchers found that among subclasses, IgG1 expression was most prominent in samples from patients with multiple myeloma, and expression of IgG1 changed significantly before, throughout, and ...
Patients re-infected with dengue virus of a serotype different from that of the initial infection are thought to be at risk of developing severe dengue hemorrhagic fever, due to the production of ...
Deleting a single amino acid (Pro230) in the lower hinge produced half-IgG1 molecules with disrupted disulfide bonds and reoriented Fab and Fc regions, highlighting the hinge’s essential role in ...
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