Lyell Immunopharma Announces Initiation of Patient Dosing in First-of-Its-Kind Phase 3 Head-To-Head CAR T-Cell Clinical Trial in Aggressive Large B-Cell Lymphoma

H2H will evaluate the efficacy and safety of rondecabtagene autoleucel (ronde-cel) versus Investigator’s choice of approved ...
Targeted Oncology

T-Cell Therapy EB103 Demonstrates Safety in B-Cell Non-Hodgkin Lymphoma

EB103 utilizes Eureka’s ARTEMIS technology, a platform designed to harness the human immune system more effectively than standard therapies. The ARTEMIS T cells are engineered to address the specific ...
Nature

Innovative CAR-T therapy destroys cancer cells without dangerous side effects

A new generation of engineered immune cell destroys cancer cells in mice 1 as effectively as conventional CAR-T-cell ...
EurekAlert!

This new understanding of T cell receptors may improve cancer immunotherapies

The gray portion of this schematic represents a nanodisc, where for the first time researchers were able to replicate the native membrane environment (red dots) of a T-cell receptor (cyan). One of the ...
GEN

Computationally Designed Receptors Help Engineered T Cells Control Tumors

Scientists at École Polytechnique Fédérale Lausanne (EPFL), and at UNIL-CHUV, University Hospital Lausanne (CHUV) and University of Lausanne (UNIL) have developed a computational method to create ...
Hosted on MSN

Engineered T-cells use natural receptors as 'brakes' to target cancer while sparing healthy tissue

A team of researchers has successfully created more effective immune cells that can fight cancer without damaging healthy tissue. "This story goes back nearly 20 years," says Prof. Paul François. This ...

Why some breast cancers evade treatment: Protein secreted by T cells may explain resistant tumors

Up to 20% of hormone receptor-positive breast cancers don't respond to antiestrogen therapies. A study led by researchers at ...