AI can help protein engineers optimize the transcription enzymes used to make mRNA-based vaccines and therapeutics, say the authors of a new study.
Trace amounts of double-stranded RNA (dsRNA) byproduct produced during in vitro transcription can interfere with downstream in vivo administration by triggering unwanted immune responses. PrimeCap™ T7 ...
Studier's T7 expression system uses the T7 promoter to "turn on" a gene of interest and the T7 RNA polymerase to transcribe that gene into messenger RNA (mRNA) so that E. coli ribosomes can use the ...
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