Medical Xpress

Study: The human body may possess a secret weapon against SARS-CoV-2

Indeed, the HLA system is controlled by genes on chromosome 6, which encode the activity of all HLA cell-surface proteins that help regulate the immune response. The Oxford team zeroed in on HLA-E ...
Medscape

Trends in HLA Antibody Screening and Identification and Their Role in Transplantation

Determining the specificity of HLA antibodies is arguably one of the most important contributions by the HLA laboratory today. For patients that have low-to-moderate levels of antibody, using a ...
ascopubs.org

Evolutionary divergence of the HLA-B genotype as a predictor of immune checkpoint inhibitor (ICI) therapy efficacy in hepatobiliary cancers.

Hepatic arterial infusion chemotherapy plus lenvatinib and PD-1 inhibitors as first-line treatment for hepatocellular carcinoma with high tumor burden and portal vein tumor thrombus. This is an ASCO ...
News Medical

Common genetic variation responsible for mediating SARS-CoV-2 asymptomatic infection

Have you ever wondered why some people never became sick from COVID-19? A study published today in Nature shows that common genetic variation among people is responsible for mediating SARS-CoV-2 ...
ascopubs.org

Assessment of Functional Status of Human Leukocyte Antigen Class I Genes in Cancer Tissues in the Context of Personalized Neoantigen Peptide Vaccine Immunotherapy

Somatic mutations in HLA genes were detected in the tumor data of five patients, and somatic HLA gene loss of heterozygosity was identified in the tumor data of five patients. Complete or partial ...